The One and Only Genetic Test for Ridge Disposition
Miroslav Hornak, Ph.D., a molecular geneticist at the Veterinary Research Institute in Brno, Czech Republic, has developed the first and only genetic test for Rhodesian Ridgeback ridge disposition in the world. JOuStore partners with Dr. Hornak to perform testing that will provide breeders with information that could reduce the occurrence of dermoid sinus and ridge abnormalities while maintaining a 96% likelihood of ridges on each puppy. Breeding a dominant homozygote with a heterozygote provides much more favorable results than breeding two heterozygotes or two homozygotes.
- Additional information
- Reviews (1)
- Genetic testing
- Free one-day (EU) or two-day (US and CA) shipping and sample pickup
- Free shipping (AU) by a local agent and sample pickup
- Buccal Swab Kit
- Tax included in price
Genetic Influence on Ridge Disposition
The distinguishing feature of a Rhodesian Ridgeback is the strip of hair along the dorsal midline growing in the opposite direction than the rest of the coat. The ridge is caused by a genetic mutation that duplicates several genes along the DNA sequence. It’s known as the “ridge gene” and is typically dominant, but has shown roughly 4% recession in heterozygous puppies.
A homozygous dog is one whose alleles are the same, either dominant (ridge gene) or recessive (no ridge). A heterozygous dog is one whose alleles are different, one ridge gene and one ridgeless. It has recently been discovered that heterozygous Rhodesian Ridgebacks can be born without a ridge due to incomplete penetrance of the gene, though this is rare.
Depending on whether the ridged parents are dominant homozygous or dominant heterozygous, the puppies may inherit two ridge genes, one ridge gene, or no ridge genes (dominant homozygous, heterozygous with >96% change of ridge, or recessive homozygous respectively). Statistically, slightly more than 25% of puppies born to two heterozygotes will be ridgeless. Without genetic testing, it is impossible to tell whether a dog is a heterozygote or homozygote.
Prevalence of Dermoid Sinus and Ridge Abnormalities
Rhodesian Ridgebacks mix are unusually prone to a condition known as dermoid sinus, which causes penetrating tunnels through the skin and deeper tissue. These cavities are prone to infection. There is also a fairly common occurrence of ridge abnormalities. Studies have revealed that there is a correlation between the ridge gene and the occurrence of either ridge abnormalities or dermoid sinus or both. Dominant homozygotes are five times more likely to be born with dermoid sinus. More testing is needed to determine the increased likelihood of ridge abnormalities in dominant homozygotes, though the correlation is evident.
Shipping and Results
We partner with DHL Express to ensure your swabs are picked up and tested within an effective timeframe. One or two-day options are available for most countries. Your swab will be picked up by a DHL agent and delivered to us by Worldwide Express. Your results will be delivered via email to ensure the fastest possible turnaround time. Countries outside the EU*, US, CA, and Australia will have an additional 30 EUR fee to cover shipping.
*EU Countries: Belgium, Bulgaria, Croatia, Denmark, Estonia, Finland, France, Ireland, Italy, Cyprus, Lithuania, Latvia, Luxembourg, Hungary, Malta, Vatican, Monaco, Germany, Netherlands, Poland, Austria, Romania, Slovakia, Slovenia, Spain, Sweden, United Kingdom.
How it Works
- Order your kit.
- Submit a GENETIC TEST: Ridge Disposition request form.
- Choose a blood or buccal swab testing kit.
- Choose the sample submission method.
- Free sample pickup.
- Receive results via email within 10 days.
Veterinary Research Institute
Veterinary Research Institute (Genetics & Reproduction) Brno, CZ